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Is alpha lipoic acid an effective anti-aging supplement?
Posted: 20 June 2008 07:49 AM   [ Ignore ]
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I saw some stories on the 5 o'clock news yesterday that alpha lipoic acid is great for anti-aging and preventing wrinkles.

Any truth to this? I'm still very young, but anything that helps prevent future premature aging..count me in!
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Posted: 20 June 2008 09:34 AM   [ Ignore ]   [ # 1 ]
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Alpha lipoic acid is a new wave of anti-oxidants that has been proven to fight free radicals in skin cells, so it would make sense that people are using it to turn back the hands of time. It works by helping to build strong collagen synthesis thus preventing wrinkles. Combining vitamin C helps the body absorb this antioxidant even further.
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Posted: 20 June 2008 10:46 AM   [ Ignore ]   [ # 2 ]
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I think the use of alpha lipoic acid (ALA) is certainly exciting, but I'd probably hold off on suggesting it "proven" to do anything. Proof in science doesn't exist...a more appropriate term may be "support." My apologies for how that may sound; its merely a pet peeve of mine.

The reason it has gained so much acclaim in the anti-aging came from the hypothesized theory of oxidation and its contribution to the aging process. See, ALA is capable of regenerating other antioxidants back to their active states: Vitamin C, Vitamin E, glutathione, and CoEnzyme Q10. I don't think you need to combine it with those agents as any of those said antioxidants in excess could actually become PRO-oxidative.

With diabetics, this agent (or particularly, its R isomer) enhances glucose uptake, inhibits glycosylation (glycation), and can improve nerve damage and reduce pain associated with that nerve damage. With people that harbor glaucoma, ALA taken at about 1/8th the diabetic dose can actually get visual aid. Hell, in a test tube - ALA actually inhibits replication of the HIV virus, though I am unaware of whether oral supplementation would have any benefit in the same disease populace.

As far as all the fashionable creams to hit the market, I remain unconvinced and don't think this merits the use of your hard-earned cash at present personally ... even in theory.

I do agree that if you are young, now - rather than later - would be the time to employ suggestive preventative strategies. In that case, I am more apt to suggest various retinol creams in terms of wrinkles and such. With sun exposure, this could prove problematic however (unsure).



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Dana Houser, MD, MHSA, CISSN

Disclaimer:  Although a Medical Doctor, my position in this online community is solely for INFORMATIONAL PURPOSES ONLY.  That said, any comments about scripts and/or referrals is strictly prohibited.

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Posted: 29 June 2008 05:23 PM   [ Ignore ]   [ # 3 ]
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I would definitely agree on the retinol creams and wrinkles. I was prescribed Retin-A when I was a teenager (for acne) and used it for about 4 years straight. To this day (36 yrs old) I routinely have people under-guess my age by 10+ years, easy. But your point on the sun is important - my face to this day will burn bright red without 30-45 SPF and a hat, and back when I was using it, there was almost nothing I could do to keep my face from burning.

I am always amazed why more women don't use Retin-A, or question it's efficacy. They always ask me about me skin when they realize my true age, when I tell them about Retin A they look stumped.
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Posted: 30 June 2008 12:37 AM   [ Ignore ]   [ # 4 ]
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Wow, your 36 and people guess your age by 10+ years younger? damn, that's impressive.

I wanna be like that too when I'm your age! I regularly use retin-a also and vitamin c serum, but I don't put it under my eyes, since it can go in and irritate my eyes.

Those 2 ingredients I've found(topically) to be the best.

Alpha lipoic acid is also something I am trying and I do believe it helps(internally) to help me look younger externally.

It is surely worth a try to anyone wanting a solution to look younger.
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Posted: 14 July 2008 12:46 AM   [ Ignore ]   [ # 5 ]
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SuperDuperBig - 29 June 2008 05:23 PM
I would definitely agree on the retinol creams and wrinkles. I was prescribed Retin-A when I was a teenager (for acne) and used it for about 4 years straight. To this day (36 yrs old) I routinely have people under-guess my age by 10+ years, easy. But your point on the sun is important - my face to this day will burn bright red without 30-45 SPF and a hat, and back when I was using it, there was almost nothing I could do to keep my face from burning.

I am always amazed why more women don't use Retin-A, or question it's efficacy. They always ask me about me skin when they realize my true age, when I tell them about Retin A they look stumped.


Thank you for sharing! I’m 29yrs old and I want to try retinol too and I hope I got a result like yours. I also wanted to try ALA but since it is not yet proven I’ll wait for more details about it first.
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